Metformin’s Hidden Brain Pathway Revealed
Published on: March 28, 2026, 11 p.m. | Source: The Indian Express
For over 60 years, metformin has been the gold standard for type 2 diabetes, primarily believed to target the liver and gut. However, a groundbreaking 2026 study published in Science Advances reveals a hidden brain-related pathway. Researchers at Baylor College of Medicine found that metformin activates SF1 neurons in the ventromedial hypothalamus via the Rap1 protein.
